Dr Andrew Harford – BAppSc (Hons), PhD

Supervising Scientist research profiles

Background

Dr Andrew Harford is a Research Scientist with the ERISS Ecotoxicology program. His role involves investigating the effects of mining effluents, metals/major ions and suspended sediments on aquatic biota. Currently, his research is focused on the effect of pulse exposures of mining-related contaminants and the development of appropriate toxicity tests to assess the impacts of suspended sediments on tropical freshwater species. He also is currently involved in a project to develop sediment quality guidelines for uranium, which includes 454-pyrosequencing of microbial communities.

His postdoctoral experience included work in the field of nanotoxicology and human-health risk assessment. Dr Harford’s PhD project involved the optimisation and application of immune function assays in high-value Australian native freshwater fishes and was the first study to assess the immunotoxicity of aquatic contaminants in native freshwater fishes.

Areas of expertise and research interests

Aquatic ecotoxicology (including freshwater and marine), sediment ecotoxicology, particulate toxicology (including suspended sediments and nanoparticles), environmental statistics and risk assessment, metagenomics and immunotoxicology.

Current key projects

  • The toxicity of uranium to sediment biota of Magela Creek backflow billabong environments
  • Direct effects of suspended sediment on tropical freshwater species
  • Toxicity of pulse-exposed magnesium to tropical freshwater species
  • Toxicity of treated pond and process waters from Ranger Uranium Mine to tropical freshwater species
  • Preliminary assessment of the toxicity of manganese to tropical freshwater species
  • The use of metagenomics to measure the impact of metal contamination in sediments on microbial communities (in collaboration with CDU)

Key publications

Harford AJ, Jones DR & van Dam RA 2012. Highly treated mine waters may require major ion addition before environmental release. Science of the Total Environment. in press, DOI: 10.1016/j.scitotenv.2012.10.054.

Van Dam RA, Trenfield MA, Markich SJ, Harford AJ, Humphrey CL, Hogan AC & Stauber JL 2012. Re-analysis of uranium toxicity data for freshwater organisms and the influence of dissolved organic carbon. Environmental Toxicology and Chemistry 31(11), 2606-2614.

van Dam RA, Harford AJ & Warne M 2012. Time to get off the fence: The need for definitive international guidance on statistical analysis of ecotoxicity data. Integrated Environmental Assessment and Management 8(2), 242-5.

Harford AJ, Hogan AC, Jones DR & van Dam RA 2011. Ecotoxicological assessment of a polyelectrolyte flocculant. Water Research 45(19), 6393-6402.

Feltis BN, O'Keefe SJ, Harford AJ, Piva TJ, Turney TW & Wright PFA 2011. Independent cytotoxic and inflammatory responses to zinc oxide nanoparticles in human monocytes and macrophages. Nanotoxicology 6(7), 762-770.

Harford AJ, Hogan AC, Tsang JJ, Parry DL, Negri AP, Adams MS, Stauber JL & van Dam RA 2011. Effects of an alumina refinery discharge and its key metal constituents at the upper thermal tolerance of: 1. The tropical diatom Nitzschia closterium. Marine Pollution Bulletin 62(3), 466-473

Negri AP, Harford AJ, Parry DL & van Dam RA 2011. Effects of an alumina refinery discharge and its key metal constituents at the upper thermal tolerance of: 2. The early life stages of the coral Acropora tenuis. Marine Pollution Bulletin. 62(3), 474-482

Cheng KL, Parry DL, Hogan AC, Markich SJ, Harford AJ & van Dam RA 2010. Uranium toxicity and speciation following chronic exposure to the tropical freshwater fish, Mogurnda mogurnda . Chemosphere 79(5), 547-554.

van Dam RA, Hogan A, McCullough C, Houston M, Humphrey C & Harford A 2010. Aquatic toxicity of magnesium sulfate, and the influence of calcium, in very low ionic concentration water . Environmental Toxicology and Chemistry 29(2), 410-421.

Hogan AC, van Dam RA, Houston MA, Harford AJ & Nou S 2009. Uranium exposure to the tropical duckweed, Lemna aequinoctialis, and pulmonate snail, Amerianna cumingi: fate and toxicity . Archives of Environmental Contamination and Toxicology. 59(2), 204-15.

Shigdar S, Harford AJ & Ward A 2009. Cytochemical characterisation of the leucocytes and thrombocytes from Murray cod (Maccullochella peelii peelii, Mitchell) . Fish and Shellfish Immunology 26(5), 731-736

van Dam RA, Harford AJ, Houston MA, Hogan AC & Negri A 2008. Tropical marine toxicity testing in Australia: A review and recommendations. Australasian Journal of Ecotoxicology 14(2/3), 55-88.

van Dam RA, Hogan AC, Harford AJ & Markich SJ 2008. Toxicity and metal speciation characterisation of waste water from an abandoned gold mine in tropical northern Australia  Chemosphere 73, 305-313

Harford AJ, O’Halloran K & Wright PFA 2007.The effect of in vitro and in vivo organotin exposures on the immune functions of Murray cod (Maccullochella peelii peelii) <.> Environmental Toxicology & Chemistry 26(8),1649-1656.

Priestly B, Harford A. & Sim M 2007.Nanotechnology: A promising new technology but how safe?  Medical Journal of Australia. 186(4), 187-188.

Harford A, Edwards J, Wright P & Priestly B 2007. Current OHS best practices for the Australian nanotechnology industry: A position paper by the NanoSafe Australia Network . The Journal of Occupational Health and Safety, Australia and New Zealand. 23(4), 315-331.

Harford AJ, O’Halloran K & Wright PFA 2006.Flow cytometric analysis and optimisation for measuring phagocytosis in three Australian freshwater fish.   Fish & Shellfish Immunology, 20(4), 562–573.

Shigdar S, Cook D, Jones P, Harford AJ & Ward A 2006. Blood cells of Murray cod Maccullochella peelii peelii (Mitchell) >. Journal of Fish Biology, 70(3), 973-980.

Harford AJ, O’Halloran K & Wright PFA 2005.The effects of in vitro pesticide exposures on the phagocytic function of four native Australian freshwater fish . Aquatic Toxicology, 75(4), 330–342.

SSD publications

More information about SSD publications is available online.

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